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Complications of Implantable Cardioverter Defibrillator and Their Potential Risk Factors in Patients with

Mohammad Taghi Hedayati Goudarzi1, Maryam Moradi2, Saeed Abrotan1

  • 1Cardiology Department, Rohani Hospital, School of Medicine, Babol University of Medical Sciences, Babol, Iran.

Cardiology Research and Practice
|January 11, 2024
PubMed

Insights

Hypertrophic cardiomyopathy patients receiving an implantable cardioverter defibrillator (ICD) experienced an 18.3% complication rate within one year. Hypertension was a significant risk factor, and inappropriate shocks were the most frequent complication.

Area of Science:

  • Cardiology
  • Medical Devices
  • Electrophysiology

Background:

  • Hypertrophic cardiomyopathy (HCM) increases risks of cardiac arrhythmia and sudden cardiac death (SCD).
  • Implantable cardioverter defibrillators (ICDs) are recommended for high-risk HCM patients but carry potential complications.
  • Understanding ICD complication prevalence and risk factors is crucial for patient management.

Purpose of the Study:

  • To determine the one-year prevalence of ICD insertion complications in HCM patients.
  • To identify baseline characteristics influencing the occurrence of these complications.
  • To analyze the impact of hypertension on ICD-related adverse events.

Main Methods:

  • Retrospective study of 71 HCM patients with ICDs.
  • Evaluation of complication rates over a one-year follow-up period.
  • Multivariate regression analysis to assess the impact of baseline characteristics.

Main Results:

  • 18.3% of patients experienced at least one complication within one year, with no mortality.
  • Inappropriate shocks were the most common complication (11.3%), followed by pneumothorax, lead failure, infection, perforation, and DVT.
  • A history of hypertension was the only significant risk factor associated with increased complication occurrence (P=0.01).

Conclusions:

  • ICD insertion in HCM patients has an 18.3% complication rate over one year.
  • Hypertension is a key predictor of ICD complications in this population.
  • Inappropriate shocks are the primary complication, highlighting the need for careful device programming and patient selection.
Abstract

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