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Hypercalcemic Crisis: A Rare Presentation of Ewing's Sarcoma
Abhijeet Haldhar1, Rajshekhar Lohar1, Saurabh S Kumbhar1
1Internal Medicine, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
Ewing sarcoma (ES), a rare adolescent cancer, can exceptionally cause hypercalcemia, leading to a crisis. This case highlights the importance of considering ES in hypercalcemia diagnosis.
Area of Science:
- Oncology
- Endocrinology
Background:
- Ewing sarcoma (ES) is a rare pediatric malignancy typically affecting long bones.
- Hypercalcemia of malignancy is common, but exceptionally rare in ES.
Observation:
- A 20-year-old female presented with chronic hip and lower limb bone pain.
- Her condition progressed to a hypercalcemic crisis.
Findings:
- This case underscores that ES, though rare, can manifest with severe hypercalcemia.
- The underlying mechanism, diagnostic challenges, and poor prognosis of ES-associated hypercalcemia are discussed.
Implications:
- Early consideration of ES in patients with unexplained hypercalcemia is crucial.
- A multidisciplinary approach is essential for managing this rare presentation of Ewing sarcoma.
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