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Updated: Jul 5, 2025

Synthesis of a Water-soluble Metal–Organic Complex Array
Published on: October 8, 2016
Total Synthesis of the Purported Structure of Branched Resin Glycosides Merremoside G and H2
1Department of Chemistry, Pohang University of Science and Technology, Cheongam-Ro 77, Nam-Gu, Pohang, Kyeongbuk 37673, Republic of Korea.
Abstract:
The first total synthesis of the purported structure of branched resin glycosides merremoside G and H2 is accomplished. A signature step is represented by the sequential transition-metal-catalyzed coupling of stable trisaccharide homoallylic alcohol and monosaccharide alkoxyallene to afford the pentasaccharide skeleton. This de novo strategy is conducted under mild conditions with no need of preactivation. In addition, it allows for efficient preparation of the target compounds in combination with late-stage functionalization.
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