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Related Concept Videos

The Effect of Aging on Tissues01:19

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Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
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Related Experiment Video

Updated: Jul 5, 2025

Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
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International Consensus on Anti-Aging Dermocosmetics and Skin Care for Clinical Practice Using the RAND/UCLA

Zoe D Draelos, Liu Wei, Mukta Sachdev

    Journal of Drugs in Dermatology : JDD
    |January 11, 2024
    PubMed
    Summary

    International experts developed practical anti-aging dermocosmetic recommendations for diverse skin types and concerns. Key ingredients like broad-spectrum sunscreen and niacinamide are advised for protection and repair across all Fitzpatrick skin types.

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    Area of Science:

    • Dermatology
    • Cosmetic Science
    • Clinical Practice

    Background:

    • Developing international recommendations for anti-aging dermocosmetics is crucial for clinical practice.
    • Essential ingredients for skin protection and repair form the foundation for advanced treatments.
    • Addressing specific skin concerns requires tailored approaches for diverse patient populations.

    Purpose of the Study:

    • To provide international recommendations on anti-aging dermocosmetics for clinical practice.
    • To establish guidelines for essential ingredients for skin protection and repair.
    • To develop recommendations for advanced products targeting specific skin concerns.

    Main Methods:

    • Seven international experts reviewed eight hypothetical case scenarios.
    • Scenarios covered diverse ages, skin issues, exposome factors, sexes, and Fitzpatrick skin types (FST).
    • The RAND/UCLA appropriateness method was used to achieve expert consensus on 17 key ingredients.

    Main Results:

    • High-factor broad-spectrum sunscreen, niacinamide, and topical antioxidants were recommended for all scenarios.
    • Tinted sunscreen with iron oxide was advised for all FST, with considerations for cosmetic acceptability in darker skin.
    • Retinols were cautioned for sensitive skin (FST V-VI), and alpha hydroxy acids post-laser treatment in FST IV-VI due to hyperpigmentation risks.

    Conclusions:

    • A practical tool was developed for dermatology consultations on anti-aging dermocosmetics.
    • Recommendations cater to diverse and inclusive patient populations, addressing all skin types and international needs.
    • The guidelines support evidence-based prescribing of dermocosmetics in daily practice.