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Flow Rate Deviation in Infusion Pump: Infusion Set Defect Enables Pump Malfunction and Considerable Accuracy

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Summary

Defective infusion sets can cause volumetric infusion pumps to deliver less medication than programmed, without any alarms. This risk of underinfusion errors threatens patient safety and accurate drug delivery.

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Area of Science:

  • Medical Devices
  • Biomedical Engineering
  • Patient Safety

Background:

  • Volumetric infusion pumps are critical for medication delivery.
  • Flow rate errors (over/underinfusion) are known issues.
  • Recent underinfusion errors were reported at a Swedish hospital.

Purpose of the Study:

  • Investigate underinfusion errors in volumetric infusion pumps.
  • Determine the effect of defective infusion sets on pump accuracy.
  • Assess the risk of undetected medication underdelivery.

Main Methods:

  • Experimental study using a gravimetric method for flow rate accuracy testing.
  • Comparison between manipulated and clinically used defective infusion sets.
  • Focus on infusion sets with visible silicone segment elongation.

Main Results:

  • Defective infusion sets caused significant accuracy deviations.
  • Pumps inaccurately reported higher infused volumes than actual delivery.
  • No alarms were triggered for reduced medication output.
  • Elongated sets led to substantial underinfusion, not reflected on the pump display.

Conclusions:

  • Defective infusion sets pose a serious risk to patient safety.
  • Underinfusion errors may go undetected by the pump and clinicians.
  • Ensuring infusion set integrity is crucial for accurate medication administration.