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Updated: Jul 5, 2025

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies
Published on: April 12, 2017
Lung relapse pattern in children with metastatic Wilms tumor
Giulia Fichera1, Gianni Bisogno2,3, Maria Carmen Affinita2,3
1Department of Neuroradiology, Pediatric Radiology Unit, University Hospital of Padova, Padua, Italy.
Abstract:
Wilms tumor is the most common pediatric renal cancer, and lungs represent the major site of metastasis and recurrence. Relapse occurs in 15%, months or years after treatment; so due to the small sample, acquiring more data about the pattern of lung relapse remains a challenge. The aim of our study was to evaluate if pulmonary relapse, detected by computed tomography (CT), occurred at the initial site of lung metastases or in a different location. According to our data, the CT pattern of lung relapse showed high probability of recurrence at the same site of initial metastasis.

