Related Experiment Video
Updated: Jul 5, 2025

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection
Published on: June 8, 2020
DNA Marker in Stool Led to a Second High-Quality Colonoscopy Within Three Months and Removal of an Undetected
Background:
In this case study, the patient first had a colonoscopy based on an incidental episode of vomiting and abdominal pain.
Materials And Methods:
Two months after recovery, a multitarget stool test (ColoAlert®) was performed and showed a known somatic mutation in the oncogene KRAS, reported to be associated with colorectal cancer. As a result, a second complete colonoscopy was performed at another center.
Results:
This procedure led to the diagnosis and removal of a later classified high-risk polyp that had been missed during the initial colonoscopy.
Conclusions:
This case report shows the use of genetic markers in stool testing has the potential to detect colon cancer in very early stages when treatment is inexpensive and effective.
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