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Related Concept Videos

The Parathyroid Glands00:59

The Parathyroid Glands

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The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...
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Hormones and Bone Tissue01:17

Hormones and Bone Tissue

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The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
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Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

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Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
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Skeleton and Calcium Homeostasis01:21

Skeleton and Calcium Homeostasis

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Calcium is not only the most abundant mineral in bone but also the most abundant mineral in the human body. Calcium ions are needed for bone mineralization, tooth health, heart rate regulation and strength of contraction, blood coagulation, the contraction of smooth and skeletal muscle cells, and the regulation of nerve impulse conduction. The average calcium level in the blood is about 10 mg/dL. When the body cannot maintain this level, a person will experience hypo or hypercalcemia.
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Appendicitis-II: Diagnostic Studies and Management01:29

Appendicitis-II: Diagnostic Studies and Management

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Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
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Tonsillitis II: Management01:26

Tonsillitis II: Management

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This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
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Related Experiment Video

Updated: Jul 5, 2025

Gasless Endoscopic Thyroidectomy via the Trans-Axillary Approach
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Gasless Endoscopic Thyroidectomy via the Trans-Axillary Approach

Published on: September 15, 2023

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Thyroiditis After Parathyroidectomy.

Rola Kwayess1, David S Cooper2, Ghada El-Hajj Fuleihan3

  • 1Division of Endocrinology, American University of Beirut Medical Center, Beirut, 1107 2020, Lebanon.

JCEM Case Reports
|January 12, 2024
PubMed
Summary
This summary is machine-generated.

Post-parathyroidectomy thyroiditis is a rare complication, often presenting with hyperthyroid symptoms. This condition is typically self-limiting and linked to thyroid manipulation during surgery.

Keywords:
hyperparathyroidismpalpation thyroiditisparathyroidectomythyrotoxicosis

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Area of Science:

  • Endocrinology
  • Surgical Complications
  • Thyroid Disorders

Background:

  • Parathyroidectomy is a common surgical procedure for hyperparathyroidism.
  • Thyroiditis following parathyroidectomy is a recognized but infrequently reported complication.
  • Clinical manifestations can vary widely, from mild symptoms to severe cardiovascular events.

Observation:

  • Two cases of post-parathyroidectomy thyroiditis are presented in patients with primary hyperparathyroidism.
  • Both patients developed hyperthyroid symptoms, confirmed by laboratory findings (suppressed TSH, elevated free T4) and low radioiodine uptake.
  • Conservative management led to symptom resolution and normalization of thyroid hormone levels.

Findings:

  • A review of 27 reported cases indicates thyroid manipulation during parathyroid surgery as the primary cause.
  • The condition is more prevalent after 4-gland parathyroidectomy for secondary or tertiary hyperparathyroidism.
  • Post-parathyroidectomy thyroiditis is generally self-limited, resolving within weeks.

Implications:

  • Recognizing thyroiditis as a potential complication of parathyroid surgery is crucial for accurate diagnosis and management.
  • Further research is needed to elucidate the pathophysiology and identify risk factors.
  • This highlights the importance of careful surgical technique and patient monitoring post-parathyroidectomy.