Adverse reaction assessment in Thailand

Area of Science:

• Pharmacovigilance
• Drug Safety Monitoring
• Public Health

Background:

• Established the National Adverse Drug Reaction Monitoring Center in Thailand.
• Focuses on collecting and analyzing drug hazard evidence.

Purpose of the Study:

• To analyze adverse drug reaction reports received by the Thai National Adverse Drug Reaction Monitoring Center.
• To identify common drug classes and reaction types.

Main Methods:

• Analysis of 711 adverse drug reaction reports collected between March 1983 and December 1985.
• Voluntary reporting system utilized for data collection.

Main Results:

• Antibiotics, anti-infectives, analgesics, antipyretics, and anti-inflammatory drugs were most frequently associated with adverse drug reactions.
• Skin reactions and gastrointestinal disorders were the most commonly reported adverse events.
• Qualitative insights were more significant than quantitative data from voluntary reports.

Conclusions:

• Adverse drug reaction monitoring is crucial for public health in Thailand.
• The voluntary reporting system, despite limitations, is valuable for identifying drug hazards.
• There is a critical need for trained personnel to enhance adverse drug reaction assessment and management.