Related Experiment Video
Updated: Aug 28, 2026

Assessing Working Memory in Children: The Comprehensive Assessment Battery for Children – Working Memory (CABC-WM)
Published on: June 12, 2017
Patterns of WISC-V Performance in Children with Congenital Heart Disease
Marsha Vasserman1,2,3, Kimberly Myers4,5, Brian L Brooks6,7,8
1Neurosciences Program, Alberta Children's Hospital, 28 Oki Drive NW, Calgary, AB, T3B 6A8, Canada. marsha.vasserman@ahs.ca.
Insights
Children with congenital heart disease (CHD) show lower cognitive performance across most areas compared to typically developing peers. Specific challenges were noted in Block Design and Digit Span, impacting overall development.
Area of Science:
- Pediatric Cardiology
- Neurodevelopmental Pediatrics
- Cognitive Psychology
Background:
- Congenital heart disease (CHD) is a prevalent birth defect, with survival rates improving due to medical advancements.
- The long-term quality of life and neurodevelopmental outcomes for children with CHD are increasingly critical areas of research.
- Understanding the cognitive impact of CHD is essential for comprehensive patient care and support.
Purpose of the Study:
- To evaluate the cognitive and intellectual performance of children with CHD using the latest Wechsler Intelligence Scale for Children (WISC-V).
- To compare the WISC-V performance of children with CHD against a normative control group.
- To identify specific patterns of cognitive strengths and weaknesses in children with CHD and explore correlations with disease variables.
Main Methods:
- Administered the Wechsler Intelligence Scale for Children, Fifth Edition (WISC-V) to a cohort of children diagnosed with congenital heart disease.
- Compared WISC-V scores (across all indices and subtests) of the CHD group to age-matched normative data.
- Analyzed patterns of impairment and investigated relationships between specific congenital heart disease characteristics and WISC-V outcomes.
Main Results:
- Children with CHD demonstrated significantly poorer performance than controls across all major WISC-V indices and most subtests, with large effect sizes.
- Specific subtests showing the highest rates of impairment in the CHD group included Block Design, Digit Span, and Similarities.
- Subtests least affected in children with CHD were Symbol Search, Picture Span, Figure Weights, and Vocabulary.
Conclusions:
- Congenital heart disease is associated with widespread cognitive deficits in children, affecting multiple intellectual domains.
- The findings highlight specific areas of cognitive vulnerability, such as visual-spatial processing and working memory, in children with CHD.
- Further research is warranted to elucidate the mechanisms underlying these cognitive differences and to develop targeted interventions for affected children.
Abstract:
Congenital heart disease (CHD) is one of the most common congenital birth defects. As surgical and interventional techniques have improved, the mortality has been greatly reduced and the focus has shifted to quality of life and long-term outcomes. The impact of CHD on development and cognition is becoming increasingly recognized. However, more research is needed to understand how children with CHD perform across various cognitive and intellectual domains. This study explored the performance of children with CHD on the newest version of the Wechsler Intelligence Scale for Children compared to normative controls. Children with CHD performed more poorly than normal controls across all indices and most subtests with large effect sizes. Additionally, we explored the patterns of impairment across indices and subtests, as well as the relationships between heard disease variables and WISC-V performance. Block design, Digit Span, and Similarities were the most commonly impaired scores in children with CHD, while Symbol Search, Picture Span, Figure Weights, and Vocabulary were least likely to be impaired.
Related Concept Videos
Pulse rhythm
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac muscle...
Mitral Stenosis II: Clinical features and Diagnostic Tests
Cardiomyopathy III: Hypertrophic Cardiomyopathy

