Patterns of WISC-V Performance in Children with Congenital Heart Disease

Marsha Vasserman1,2,3, Kimberly Myers4,5, Brian L Brooks6,7,8

  • 1Neurosciences Program, Alberta Children's Hospital, 28 Oki Drive NW, Calgary, AB, T3B 6A8, Canada. marsha.vasserman@ahs.ca.

Pediatric Cardiology
|January 12, 2024
PubMed

Insights

Children with congenital heart disease (CHD) show lower cognitive performance across most areas compared to typically developing peers. Specific challenges were noted in Block Design and Digit Span, impacting overall development.

Area of Science:

  • Pediatric Cardiology
  • Neurodevelopmental Pediatrics
  • Cognitive Psychology

Background:

  • Congenital heart disease (CHD) is a prevalent birth defect, with survival rates improving due to medical advancements.
  • The long-term quality of life and neurodevelopmental outcomes for children with CHD are increasingly critical areas of research.
  • Understanding the cognitive impact of CHD is essential for comprehensive patient care and support.

Purpose of the Study:

  • To evaluate the cognitive and intellectual performance of children with CHD using the latest Wechsler Intelligence Scale for Children (WISC-V).
  • To compare the WISC-V performance of children with CHD against a normative control group.
  • To identify specific patterns of cognitive strengths and weaknesses in children with CHD and explore correlations with disease variables.

Main Methods:

  • Administered the Wechsler Intelligence Scale for Children, Fifth Edition (WISC-V) to a cohort of children diagnosed with congenital heart disease.
  • Compared WISC-V scores (across all indices and subtests) of the CHD group to age-matched normative data.
  • Analyzed patterns of impairment and investigated relationships between specific congenital heart disease characteristics and WISC-V outcomes.

Main Results:

  • Children with CHD demonstrated significantly poorer performance than controls across all major WISC-V indices and most subtests, with large effect sizes.
  • Specific subtests showing the highest rates of impairment in the CHD group included Block Design, Digit Span, and Similarities.
  • Subtests least affected in children with CHD were Symbol Search, Picture Span, Figure Weights, and Vocabulary.

Conclusions:

  • Congenital heart disease is associated with widespread cognitive deficits in children, affecting multiple intellectual domains.
  • The findings highlight specific areas of cognitive vulnerability, such as visual-spatial processing and working memory, in children with CHD.
  • Further research is warranted to elucidate the mechanisms underlying these cognitive differences and to develop targeted interventions for affected children.

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