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Updated: Jul 5, 2025

An In Vitro Approach to Photodynamic Therapy
Published on: August 17, 2018
Inflammatory linear verrucous epidermal nevus in groin and labia with claudication: Successfully treated with
Li Wei1, Lu Yu2, Lingyun Zou3
1Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Department of Dermatology, Beijing, China.
Significance:
Inflammatory linear verrucous epidermal nevus (ILVEN) is an uncommon type of epidermal nevus and is refractory to therapy. We report the effectiveness of photodynamic therapy (PDT) for treating ILVEN with claudication in a young girl.
Additional Contributions:
We thank the patient for granting permission to publish this information.
Approach:
Aminolaevulinic Acid Hydrochloride (ALA) photodynamic therapy (PDT) was applied six times in 1-month interval.
Results:
Most lesions and pruritus have subsided markedly, with mild scarring and a marked reduction in claudication.
Conclusions:
ALA PDT might be an effective and promising treatment for ILVEN in the future.

