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The prevalence of bleeding after percutaneous coronary interventions: A systematic review and meta-analysis
Reza Heidary Moghadam1, Aida Mohammadi2, Nader Salari3
1Department of Department of Cardiology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Insights
Bleeding is a significant complication following percutaneous coronary intervention (PCI). This meta-analysis found a 4.4% prevalence, emphasizing the need for attention to PCI-related bleeding risks.
Area of Science:
- Cardiology
- Interventional Cardiology
- Public Health
Background:
- Bleeding is a frequent complication after percutaneous coronary intervention (PCI).
- Understanding the prevalence of bleeding is crucial for patient safety and healthcare management.
- This study aimed to quantify bleeding risk post-PCI.
Approach:
- A systematic review and meta-analysis was conducted.
- Searched multiple databases (Embase, PubMed, Scopus, WoS, etc.) from 1989-2023.
- Analyzed 8 studies with 397,298 participants using random effects due to high heterogeneity (I²: 97.8%).
Key Points:
- The overall prevalence of bleeding after PCI was determined to be 4.4% (95% CI: 2-9.1).
- High heterogeneity among studies indicates variability in reported bleeding rates.
- The findings underscore the clinical significance of bleeding as a post-PCI complication.
Conclusions:
- A notable prevalence of bleeding occurs after PCI.
- Health policymakers must address PCI-associated complications.
- Interventional cardiologists need to focus on managing and controlling bleeding events.
Background:
Bleeding is a common complication associated with percutaneous coronary intervention (PCI). The aim of this study was to determine the prevalence of bleeding after PCI through a systematic review and meta-analysis.
Methods:
The systematic review and meta-analysis covered the period from 1989 to 2023. Multiple databases, including Embase, PubMed, Scopus, Web of Sciences (WoS), MagIran, Scientific Information Database (SID), and Google Scholar, were searched using validated keywords with MeSH and Emtree. The I2 index was used to check for heterogeneity among studies.
Results:
The review of 8 studies, with a sample size of 397,298 participants, showed high heterogeneity (I2: 97.8 %). Therefore, the random effects method was used to analyze the results. The prevalence of bleeding after intervention in percutaneous coronary arteries was reported to be 4.4 % (95%CI: 2-9.1).
Conclusion:
This meta-analysis showed a significant prevalence of bleeding after PCI, highlighting the need for health policymakers to pay more attention to the complications associated with PCI. Interventional cardiologists should consider the effective factors in these bleeding and how to treat and control them due to the importance of this complication.
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