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Healthcare Associated Infections II: Preventive Measures

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Updated: Jul 5, 2025

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Published on: August 30, 2018

Regulating antimicrobial use within hospitals: A qualitative study.

Jennifer Broom¹, Alex Broom², Katherine Kenny²

¹Sunshine Coast University Hospital, Sunshine Coast Hospital and Health Service, 6 Doherty Street, Birtinya, QLD, Australia; University of Queensland, Brisbane, QLD, Australia.

Infection, Disease & Health

|January 12, 2024

Summary

This summary is machine-generated.

Hospital managers and clinicians navigate antimicrobial stewardship regulations, facing challenges in meeting standards versus driving systemic change for antimicrobial resistance. Meaningful optimisation requires resources, buy-in, and engagement.

Keywords:

Accreditation Antimicrobial resistance Antimicrobial stewardship Qualitative research Regulation

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Published on: December 14, 2020

Area of Science:

Health Services Research
Infectious Diseases
Healthcare Management

Background:

Antimicrobial resistance (AMR) is a growing global health threat.
Regulatory structures aim to improve antimicrobial stewardship (AMS) in hospitals.
Understanding stakeholder experiences is crucial for effective AMR strategies.

Purpose of the Study:

To examine how hospital managers and clinicians experience regulatory structures and processes for AMS and AMR.
To identify perceived requirements for effective antimicrobial optimisation within hospitals.

Main Methods:

Qualitative study involving 42 hospital managers and clinicians.
Conducted in three Australian hospitals.
Data collected through individual in-depth interviews and analysed using thematic analysis.

Main Results:

Participants reported increased focus on AMR due to regulatory requirements.
Concerns were raised about bureaucratic compliance over systemic change.
Effective antimicrobial optimisation requires top-down support, resources, and medical engagement.

Conclusions:

A tension exists between regulatory demands and genuine systemic change in hospitals.
Current systems may meet requirements without addressing underlying AMR concerns.
Potent regulatory structures for AMR need resourcing, multi-level buy-in, and integrated strategies.