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Related Experiment Video

Updated: Jul 5, 2025

Sterile Pericarditis in Aachener Minipigs As a Model for Atrial Myopathy and Atrial Fibrillation
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A self-powered intracardiac pacemaker in swine model.

Zhuo Liu1,2, Yiran Hu3,4, Xuecheng Qu1,5

  • 1Beijing Key Laboratory of Micro-nano Energy and Sensor, Beijing Institute of Nanoenergy and Nanosystems, Chinese Academy of Sciences, 101400, Beijing, China.

Nature Communications
|January 13, 2024
PubMed

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Summary

Researchers developed a battery-free, self-powered intracardiac pacemaker using cardiac motion. This innovative device, implanted via catheter, converts heart movement into electricity to treat arrhythmia in animal models.

Area of Science:

  • Bioelectronic devices
  • Biomedical engineering
  • Energy harvesting

Background:

  • Implantable bioelectronic devices require reliable power sources.
  • Cardiac motion presents a potential source of biomechanical energy.
  • Current pacemakers face limitations related to battery life and replacement.

Purpose of the Study:

  • To develop a battery-free, self-powered intracardiac pacemaker.
  • To utilize triboelectrification and electrostatic induction for energy conversion.
  • To evaluate the device's efficacy in treating arrhythmia in large animal models.

Main Methods:

  • A capsule-shaped device was designed for transcatheter implantation in the right ventricle.
  • The device leverages the coupled effect of triboelectrification and electrostatic induction.

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  • Implantation was performed in swine via the intravenous route, followed by a three-week observation period.
  • Main Results:

    • The self-powered intracardiac pacemaker was successfully implanted and maintained endocardial pacing function.
    • The device effectively converted cardiac motion energy into electrical energy.
    • In vivo measurements yielded an open circuit voltage of approximately 6.0 V and a short circuit current of 0.2 μA.

    Conclusions:

    • This study demonstrates a novel approach for battery-free cardiac pacing.
    • The developed device offers a promising solution for powering implantable bioelectronic devices.
    • This technology may overcome energy limitations in pacemakers and other medical devices for therapy and sensing.