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Updated: Jul 5, 2025

Employing Digital Droplet PCR to Detect BRAF V600E Mutations in Formalin-fixed Paraffin-embedded Reference Standard Cell Lines
Published on: October 8, 2015
Prognostic Value of BRAF Mutation in Glioblastoma
Ayesha Sohail1, Qurat-Ul-Ain Virani1, Hafiza Fatima Aziz1
1Section of Neurosurgery, Department of Surgery, Aga Khan University, Karachi, Pakistan.
Abstract:
With advances in molecular genetics, exploring targetable mutations for treating glioblastoma (GBM) patients, has become a centre of interest in modern day neuropathology. BRAF mutation has been extensively reported in several brain tumours. Recent studies report identification of BRAF mutation in GBM patients, especially isocitrate dehydrogenase wildtype glioblastomas (IDH-WT GBM), and its potential role in patient outcomes. Here we discuss the existing literature on the prognostic value of BRAF mutation in GBM.
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