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Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment

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Published on: September 20, 2020

Multimodal Exercise and Cognitive Training Program Improves Cognitive Function in Amnestic Mild Cognitive Impairment.

Jennifer Kaci Fairchild¹, Jonathan Myers², Peter Louras¹

¹VISN 21 Mental Illness Research, Education, and Clinical Center (JKF, PL, MWM, JH, JY), Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304; Department of Psychiatry and Behavioral Sciences (JKF, PL, BJ, MWM, JH, JY), Stanford University School of Medicine, Stanford, CA 94305.

The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry

|January 14, 2024

Summary

This summary is machine-generated.

This study found that combined exercise and cognitive training improved memory and executive function in older adults with mild cognitive impairment. The combined aerobic and resistance exercise group also showed gains in processing speed and functional capacity.

Keywords:

Aerobic exercise Veterans cognitive training mild cognitive impairment resistance exercise

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Area of Science:

Gerontology
Neuroscience
Exercise Science

Background:

Older adults with amnestic mild cognitive impairment (aMCI) often experience cognitive decline.
Interventions combining physical exercise and cognitive training are being explored to mitigate cognitive impairment.

Purpose of the Study:

To investigate the preliminary efficacy of a combined physical exercise and cognitive training intervention for older adults diagnosed with aMCI.
To compare the effects of a combined aerobic and resistance exercise plus cognitive training (CARE+CT) versus stretching exercise plus cognitive training (SE+CT).

Main Methods:

A randomized clinical trial involving 72 community-dwelling volunteers with aMCI.
Participants were assigned to either CARE+CT or SE+CT interventions.
Primary outcomes included word list and name-face recall; secondary outcomes assessed cognitive domains, VO2 max, and functional capacity.

Main Results:

All participants showed improvements in delayed word list recall, learning, memory, and executive function.
The CARE+CT group demonstrated significant improvements in processing speed and functional capacity.
APOE4 status influenced the cognitive benefits observed in the SE+CT group.

Conclusions:

Preliminary evidence supports the use of combined exercise and cognitive training interventions for individuals with aMCI.
Further research is necessary to elucidate the underlying mechanisms and test these interventions in diverse populations.