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Application of Nanohybrid Substrates with Layer-by-Layer Self-Assembling Properties to High-Sensitivity
Yan-Feng Chen1, Yen-Chen Lee1, Wen-Wei Lin1
1Department of Materials Science and Engineering, National Taiwan University of Science and Technology, Taipei 10607, Taiwan.
ACS Omega
|January 15, 2024
Summary
This study developed large-area, high-sensitivity surface-enhanced Raman scattering (SERS) substrates using gold nanoparticles and graphene oxide. These novel nanohybrid materials offer excellent detection limits for environmental and biological applications.
Area of Science:
- Materials Science
- Nanotechnology
- Analytical Chemistry
Background:
- Developing sensitive and large-area substrates is crucial for surface-enhanced Raman scattering (SERS).
- Controlling nanoparticle size and distribution on substrates remains a challenge.
- Graphene oxide (GO) offers unique properties for nanomaterial stabilization and assembly.
Purpose of the Study:
- To prepare and investigate novel large-area, high-sensitivity SERS substrates.
- To utilize organic/inorganic nanohybrid dispersants for stabilizing gold nanoparticles (AuNPs) on GO.
- To explore the self-assembly and SERS performance of the developed AuNP/GO nanohybrids.
Main Methods:
- Synthesized AuNPs stabilized by a triblock copolymer and GO.
- Employed solution drop-casting for depositing AuNP/GO nanohybrids onto glass substrates.
- Annealed the substrates to remove the copolymer and characterized the nanohybrid structure using electron microscopy.
Main Results:
- Achieved uniform AuNP sizes (25-35 nm) stabilized by GO/copolymer.
- Demonstrated regular lamellar arrangement of AuNP/GO nanohybrids due to GO's self-assembly.
- Obtained a high SERS enhancement factor (EF) of up to 3.5 × 10^6 for rhodamine 6G.
- Reached detection limits as low as 10^-10 M for various analytes, including dyes and adenine.
Conclusions:
- AuNP/copolymer/GO nanohybrids form effective large-area flexible SERS substrates.
- The 3D hot-junction effect generated by thin GO nanosheets enhances SERS sensitivity.
- These substrates show significant potential for environmental monitoring and biological detection.
