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The triphasics: insights for effective clinical use.

E Q Youngkin, L G Miller

    The Nurse Practitioner
    |February 1, 1987
    PubMed
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    Newer triphasic oral contraceptives mimic the menstrual cycle, reducing hormone dosage and side effects. These formulations enhance menstrual control and safety for improved patient care.

    Area of Science:

    • Reproductive Health
    • Endocrinology
    • Pharmacology

    Background:

    • Three triphasic oral contraceptive formulations are commonly used in the US: Ortho-Novum 7/7/7, Tri-Norinyl, and Triphasil.
    • These formulations are designed to more closely replicate the natural menstrual cycle.
    • They aim to decrease the total hormone dose, reduce menstrual irregularities, and minimize side effects while ensuring efficacy and safety.

    Purpose of the Study:

    • To describe the characteristics of widely used triphasic oral contraceptive preparations.
    • To review their mechanisms of action, efficacy, and safety profiles.
    • To provide guidance for clinical practice regarding side effects, safety, and menstrual control.

    Main Methods:

    • Review of existing literature and product information on Ortho-Novum 7/7/7, Tri-Norinyl, and Triphasil.
    Keywords:
    AcneBiologyBleedingBody WeightContraceptionContraception ContinuationContraception FailureContraceptive Agents, Estrogen--side effectsContraceptive Agents, Female--side effectsContraceptive Agents, Progestin--side effectsContraceptive Agents--side effectsContraceptive EffectivenessContraceptive Methods--side effectsContraceptive UsageCounselingDepressionDermatological EffectsDiseasesDrugsEndocrine SystemEthinyl Estradiol--side effectsEvaluationFamily PlanningGastrointestinal EffectsGenital Effects, FemaleGenitaliaGenitalia, FemaleHeadacheHormonesLevonorgestrel--side effectsMeasurementMenstruation DisordersMetabolic EffectsMetrorrhagiaNeurologic EffectsNorethindrone--side effectsOral Contraceptives, Low-dose--side effectsOral Contraceptives--side effectsPhysiologyProgram ActivitiesQualitative EvaluationReproductive Control AgentsResearch MethodologySigns And SymptomsUrogenital EffectsUrogenital SystemUse-effectiveness

    Related Experiment Videos

  • Analysis of hormonal manipulation and its impact on the menstrual cycle.
  • Evaluation of clinical data concerning efficacy, side effects, and safety.

    • Main Results:

    • Triphasic oral contraceptives offer improved menstrual cycle regulation and reduced hormonal exposure compared to older formulations.
    • These preparations demonstrate efficacy and safety comparable to other oral contraceptives.
    • Key areas of concern include managing potential side effects and ensuring proper patient counseling.

    Conclusions:

    • Triphasic oral contraceptives provide a valuable option for women seeking effective contraception with enhanced menstrual control and reduced side effects.
    • Understanding their mechanisms and clinical considerations is crucial for healthcare providers.
    • Optimal patient care involves informed administration, counseling, and management of these newer oral contraceptives.