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Induction of Drug-Induced, Autoimmune Hepatitis in BALB/c Mice for the Study of Its Pathogenic Mechanisms

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Case of Autoimmune Hepatitis.

Romman Fatima¹, Viquasuddin Mohammed¹, Afra Fatima²

¹Department of Internal Medicine Olive Hospital, Hyderabad, Telangana, India.

Euroasian Journal of Hepato-Gastroenterology

|January 15, 2024

Summary

Autoimmune hepatitis (AIH) is a chronic liver disease more common in women, potentially leading to cirrhosis. This case highlights a 62-year-old female diagnosed with AIH and cirrhosis, successfully treated with corticosteroids.

Area of Science:

Hepatology
Immunology
Internal Medicine

Keywords:

Autoimmune hepatitis Bilirubin Biopsy Case report Cirrhosis of the liver

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Background:

Autoimmune hepatitis (AIH) is a chronic liver disease characterized by inflammation and potential progression to fibrosis and cirrhosis.
AIH predominantly affects females and presents with varied symptoms, from fatigue to jaundice, with up to a third diagnosed with cirrhosis.
Current management involves corticosteroids and immunosuppressants, but treatment response varies, necessitating long-term therapy for many.