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Depression among Patients with Chronic Hepatitis B: A Cross-sectional Study in a Tertiary Hospital of Bangladesh

Merina Rahman1, Sheikh Mohammad Noor-E-Alam2, Md Abdur Rahim2

  • 1Department of Hepatology, Khulna Medical College and Hospital, Khulna, Dhaka, Bangladesh.

Euroasian Journal of Hepato-Gastroenterology
|January 15, 2024
PubMed

Insights

Patients with chronic hepatitis B (CHB) experience higher rates of depression compared to healthy individuals. This study found moderate and severe depression significantly more prevalent in CHB patients, particularly among females.

Area of Science:

  • Hepatology
  • Psychiatry
  • Public Health

Background:

  • Chronic hepatitis B (CHB) presents significant mental health challenges beyond physical symptoms.
  • Depression is a common comorbidity in patients managing chronic liver disease.

Purpose of the Study:

  • To evaluate depression levels in CHB patients.
  • To compare depression prevalence between CHB patients and healthy controls.
  • To identify factors associated with depression in CHB.

Main Methods:

  • A comparative cross-sectional study was conducted.
  • 90 CHB patients and 90 HBsAg-negative healthy controls participated.
  • Depression incidence and severity were assessed and compared.

Main Results:

  • 57.8% of CHB patients exhibited depression versus 35.6% of controls (p<0.05).
  • Moderate and severe depression were significantly higher in CHB patients.
  • Depression in CHB patients was more prevalent in females.

Conclusions:

  • CHB patients demonstrate a significantly higher prevalence of depression.
  • Mental health screening and support are crucial for CHB management.
  • Further research into gender-specific mental health impacts in CHB is warranted.
Abstract

Keywords:
DepressionHepatitis BMental healthPatient

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