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Updated: Jul 5, 2025

Single-Cell Characterization of Calcium Influx and HIV-1 Infection using a Multiparameter Optofluidic Platform
Published on: May 18, 2021
Pediatric human immunodeficiency virus infection presenting as symptomatic hypocalcemia
Shambhavi1, Nikita1, Akshay Shankar1
1Department of Pediatrics, Shaheed Nirmal Mahto Medical College, Dhanbad, Jharkhand, India.
Insights
Mother-to-child transmission of human immunodeficiency virus (HIV) often leads to late diagnosis in children. This case highlights severe hypocalcemia as a presenting symptom, underscoring the need for calcium screening in pediatric HIV.
Area of Science:
- Pediatric infectious diseases
- Nutritional deficiencies in immunocompromised children
- Clinical case studies in virology
Background:
- Mother-to-child transmission (MTCT) of human immunodeficiency virus (HIV) remains a significant global health issue, impacting thousands of children annually.
- Children infected with HIV are frequently diagnosed late, often presenting with advanced disease manifestations such as protein energy malnutrition.
- Early identification of opportunistic infections and metabolic derangements is crucial for timely intervention and improved outcomes in pediatric HIV.
Abstract:
Mother to child transmission still accounts for thousands of children being affected with human immunodeficiency virus (HIV) yearly. These children are often detected late in their disease course, most commonly presenting as protein energy malnutrition. Here we present a unique pediatric case who presented with severe symptomatic hypocalcemia. The case highlights the importance of vitamin D and calcium screening in this subgroup of HIV patients.
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