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Published on: December 19, 2020
Prognostic Factors for Predicting Post-COVID-19 Condition in Patients With COVID-19 in an Outpatient Setting
Myeong Geun Choi1, Young Woong Joo2, Min-Ho Kim3
1Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Ewha Womans University Mokdong Hospital, Ewha Womans University College of Medicine, Seoul, Korea.
Not using antiviral drugs and low vitamin D levels are key factors prolonging COVID-19 symptoms in outpatients. Early antiviral treatment and vitamin D supplementation may shorten symptom duration and reduce post-COVID-19 conditions.
Area of Science:
- Infectious Diseases
- Pulmonology
- Public Health
Background:
- Limited understanding of prognostic factors for symptom duration in non-hospitalized COVID-19 patients.
- Need to identify predictors for prolonged post-COVID-19 conditions.
Purpose of the Study:
- Investigate prognostic factors influencing symptom duration in COVID-19 outpatients.
- Identify predictors for developing post-COVID-19 conditions.
Main Methods:
- Analysis of data from 257 mild COVID-19 outpatients (April-December 2022).
- Symptom duration measured from diagnosis to resolution.
- Collected laboratory and pulmonary function test data.
Main Results:
- Median symptom duration was 57 days.
- Prolonged symptoms correlated with no antiviral use, leukocytosis, low 25(OH)D3, reduced FVC (<90%), dyspnea, and anxiety/depression.
- Not using antivirals, low vitamin D, and dyspnea were independent poor prognostic factors.
Conclusions:
- Non-use of antivirals, low vitamin D, leukocytosis, reduced FVC, dyspnea, and anxiety/depression predict post-COVID-19 conditions.
- Antiviral use during acute phase and vitamin D may reduce symptom duration.
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