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Mixed Adeno-Neuroendocrine Neoplasms: Two Cases, One Institution
Casey Paterson1, Gabrielle Perrotti2, Bakhtawar Mushtaq2
1Abington Memorial Hospital-Jefferson Health Department of Surgery, Abington, PA. (Drs. Paterson, Perrotti, Mushtaq, and Heilman).
Mixed neuroendocrine non-neuroendocrine neoplasms (MiNENs) are rare gastrointestinal tumors. This report details two rectal MiNEN cases, highlighting the need for further research into their epidemiology and treatment.
Area of Science:
- Gastroenterology
- Oncology
- Pathology
Background:
- Epithelial tumors with both neuroendocrine and nonendocrine components are rare and aggressive.
- These neoplasms were termed "mixed adeno-neuroendocrine carcinomas" (MANECs) in 2010 and later renamed "mixed neuroendocrine non-neuroendocrine neoplasms" (MiNENs).
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