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SARS-CoV-2 associated septic venous cavernous sinus thrombosis: A case report
Mark A Colantonio1, Jessica N Arvon1, Nicholas Koenig1
1Department of Medicine, Division of Pulmonary, Critical Care & Sleep Medicine, West Virginia University School of Medicine, Morgantown, WV 26506 USA.
Insights
Cavernous sinus thrombosis (CST) is a serious condition linked to infections and clotting issues. This case highlights a rare delayed CST and ophthalmic vein thrombosis following COVID-19 infection.
Area of Science:
- Neurology
- Infectious Diseases
- Vascular Medicine
Background:
- Cavernous sinus thrombosis (CST) is a rare but severe condition often caused by infection or coagulation disorders.
- COVID-19 has been associated with an increased risk of thromboembolic events due to endothelial and clotting factor dysfunction.
Observation:
- A case of cavernous sinus thrombosis (CST) and subsequent ophthalmic vein thrombosis is presented.
- The patient had a preceding COVID-19 infection.
- Diagnosis was confirmed using facial computed tomography (CT) scan.
Findings:
- The study reports a delayed presentation of cavernous sinus thrombosis and ophthalmic vein thrombosis.
- These thrombotic events were associated with a prior COVID-19 infection, suggesting a potential link between viral infection and hypercoagulability.
Implications:
- Clinicians must consider COVID-19 as a potential cause for hypercoagulable states and associated thrombotic complications.
- Early recognition and management of such complications are crucial for patient outcomes.
- This case underscores the importance of a broad differential diagnosis in patients presenting with thrombotic events, especially in the context of recent viral infections.
Abstract:
Cavernous sinus thrombosis (CST) is a life-threatening condition occurring due to an active infection, coagulation abnormalities, and trauma. Thromboembolic events are known complications secondary to novel coronavirus disease-19 (COVID-19) due to dysfunction in endothelial function and clotting factor dysfunction. We report a case of cavernous sinus thrombosis and delayed ophthalmic vein thrombosis associated with a preceding COVID-19 infection confirmed with a facial computed tomography (CT) scan. Clinicians should have a broad differential in patients with hypercoagulable states, as complications secondary to COVID-19 can be life-threatening.
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