SARS-CoV-2 associated septic venous cavernous sinus thrombosis: A case report

Mark A Colantonio1, Jessica N Arvon1, Nicholas Koenig1

  • 1Department of Medicine, Division of Pulmonary, Critical Care & Sleep Medicine, West Virginia University School of Medicine, Morgantown, WV 26506 USA.

Radiology Case Reports
|January 17, 2024
PubMed

Insights

Cavernous sinus thrombosis (CST) is a serious condition linked to infections and clotting issues. This case highlights a rare delayed CST and ophthalmic vein thrombosis following COVID-19 infection.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Vascular Medicine

Background:

  • Cavernous sinus thrombosis (CST) is a rare but severe condition often caused by infection or coagulation disorders.
  • COVID-19 has been associated with an increased risk of thromboembolic events due to endothelial and clotting factor dysfunction.

Observation:

  • A case of cavernous sinus thrombosis (CST) and subsequent ophthalmic vein thrombosis is presented.
  • The patient had a preceding COVID-19 infection.
  • Diagnosis was confirmed using facial computed tomography (CT) scan.

Findings:

  • The study reports a delayed presentation of cavernous sinus thrombosis and ophthalmic vein thrombosis.
  • These thrombotic events were associated with a prior COVID-19 infection, suggesting a potential link between viral infection and hypercoagulability.

Implications:

  • Clinicians must consider COVID-19 as a potential cause for hypercoagulable states and associated thrombotic complications.
  • Early recognition and management of such complications are crucial for patient outcomes.
  • This case underscores the importance of a broad differential diagnosis in patients presenting with thrombotic events, especially in the context of recent viral infections.

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