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Cameron Lesions With Severe Anemia: A Case Report.
Mathangi Rajaram-Gilkes1, Juan J Cardona2, Aishwarya J Gilkes3
1Department of Medical Education, Geisinger Commonwealth School of Medicine, Scranton, USA.
Cureus
|January 17, 2024
Summary
Cameron lesions found in large hiatus hernias can cause severe anemia in elderly patients. Early detection via chest X-rays and endoscopy is crucial for diagnosing this often-overlooked cause of upper GI bleeding.
Area of Science:
- Gastroenterology
- Internal Medicine
- Geriatrics
Background:
- Hiatus hernia (HH) is a common condition, particularly in the elderly.
- Microcytic hypochromic anemia can be a sign of chronic gastrointestinal blood loss.
- Cameron lesions are mucosal defects found in the gastroesophageal junction within a hiatus hernia.
Observation:
- An elderly patient presented with severe anemia.
- Endoscopic examination revealed Cameron lesions within a large paraesophageal hiatus hernia.
- These lesions were identified as the likely cause of chronic blood loss.
Findings:
- Cameron lesions are an under-recognized cause of chronic upper gastrointestinal bleeding (UGIB).
- They are frequently found in elderly patients with large hiatus hernias presenting with anemia.
- This association highlights the need to consider Cameron lesions in the differential diagnosis of UGIB.
Implications:
- Increased physician awareness of Cameron lesions is necessary for prompt diagnosis and management.
- Screening with chest X-rays (CXR) can aid in early detection of hiatus hernias.
- Esophagogastroduodenoscopy (EGD) is essential for confirming Cameron lesions and guiding treatment.

