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Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice
Published on: September 19, 2016
[Natural immunity of the pupils in a secondary vocational and technical school for rubber and plastics]
Abstract:
In connection with the reconstruction of the educational system and occupational training of the youths, the problem of the effect of the occupational factors on the organism of the juveniles is of exceptional importance. The search of early changes by the application of immunological tests in that aspect is very rational. The state of microflora of the deep layers of the skin, the microbic contamination of nasal mucosa have been studied as well as the content of complement in serum and serum immunoglobulins G, A and M and the phagocytosis in the students from SPTS. The experimental subjects have exposed to a complex of toxic-chemical substances with different intensity during their occupational training and practice. It has been established that the training under the specific conditions for mastering the specialty has led to a slight decrease of the antimicrobic resistance and reduction of the phagocytic function of leukocytes, not affecting the humoral factors of natural immunity.
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