On the accuracy of source localisation in cardiac measurements

This paper describes a localisation study of the sources of bioelectrical activity in the human heart. In particular, the atrial activation (P wave) and the activation of an extra pre-excitation area in the WPW syndrome are investigated. Different models based on the current multipole expansion are used to calculate the inverse solution. A comparison between calculated results, invasive electrophysiological studies and known physiological data is performed. The best results were obtained by the current multipole model with dipole and quadrupole terms. Non-invasive localisation of cardiac electric sources can be useful in studies of arrhythmia patients in the future.