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Organic nanomotors: emerging versatile nanobots.
Jingjun Jin1, Yan Li1, Shuai Wang2
1School of Chemical Engineering and Technology, Tianjin University, Tianjin, 300072, China. xiboyan@tju.edu.cn.
Nanoscale
|January 17, 2024
Summary
Synthetic organic nanomotors offer efficient, stimulus-responsive cargo delivery. This review details their propulsion, behavior, and anticancer applications, paving the way for future innovations in nanotechnology.
Area of Science:
- Nanotechnology
- Materials Science
- Biomedical Engineering
Background:
- Artificial nanomotors are nanoscale machines converting energy into motion.
- Recent advances enable stimulus-responsive autonomous movement for transport and cargo delivery.
- Programmable kinetic systems for powering nanomotors are gaining attention.
Purpose of the Study:
- To review recent synthetic organic nanomotors powered exclusively by organic kinetic systems.
- To illustrate their stimulus-responsive propulsion mechanisms and motion behaviors.
- To highlight their performance in antitumor therapy and propose future perspectives.
Main Methods:
- Review of recent literature on synthetic organic nanomotors.
- Analysis of propulsion mechanisms based on organic molecules or aggregates.
- Evaluation of motion behaviors and therapeutic applications, particularly in cancer treatment.
Main Results:
- Detailed examples of organic nanomotors with self-propelled motion are presented.
- Stimulus-responsive propulsion and diverse motion behaviors are illustrated.
- Performance data in antitumor therapy showcases their therapeutic potential.
Conclusions:
- Synthetic organic nanomotors represent a promising advancement in nanotechnology.
- Continued innovation in organic kinetic systems will expand their applications.
- These nanomotors are poised for significant impact in areas like targeted drug delivery and cancer therapy.

