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Monkeypox in a patient with HIV: case report
Alex Omar Franco Lacato1,2, Nataniel Aldo Chaparro Mérida3, Dayany Moreno Samper4
1Hospital Universitario San Juan de Dios, Santa Cruz de la Sierra, Bolivia.
Revista Peruana De Medicina Experimental Y Salud Publica
|January 17, 2024
Summary
This case study highlights a patient with co-infection of monkeypox (Mpox), HIV, syphilis, and gonorrhea. Early diagnosis and tailored treatment led to patient recovery.
Area of Science:
- Infectious Diseases
- Virology
- Dermatology
Background:
- Monkeypox (Mpox) is a zoonotic viral disease endemic to parts of Africa.
- Global outbreaks of Mpox have been reported in non-endemic regions since May 2022.
- Co-infections with other sexually transmitted infections can complicate Mpox diagnosis and management.
Observation:
- A patient with HIV presented with Mpox symptoms, including rash predominantly in the gluteal region, cervical lymphadenopathy, and infectious proctitis.
- Co-infections with Treponema pallidum (syphilis) and Neisseria gonorrhoeae were identified through serology and rectal discharge culture.
Findings:
- Real-time polymerase chain reaction (RT-PCR) confirmed Mpox diagnosis from skin lesion samples.
- The patient received targeted antibiotic therapy for gonorrhea and syphilis, alongside symptomatic and immunomodulatory treatments.
Implications:
- This case highlights the importance of considering co-infections in immunocompromised patients presenting with Mpox.
- Integrated diagnostic and treatment strategies are crucial for managing complex infectious disease presentations in non-endemic settings.
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