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Antioxidant therapy for hepatic diseases: a double-edged sword
Sayandeep K Das1, Savitri M Nerune1, Kusal K Das2
1Department of Pathology, Shri B. M. Patil Medical College, Hospital and Research Centre, BLDE (Deemed to be University), Vijayapur, Karnataka, India.
Journal of Basic and Clinical Physiology and Pharmacology
|January 18, 2024
Summary
Antioxidants show promise for liver disease, but human trials are inconclusive. Further research is needed to understand their benefits, risks, and interactions with genetics and other drugs.
Area of Science:
- Hepatology
- Biochemistry
- Genetics
Background:
- Liver diseases are complex and significantly influenced by oxidative stress.
- Oxidative stress plays a critical role in the susceptibility, progression, and treatment response of liver conditions.
Conclusions:
- Further research is essential to establish the clinical benefits of antioxidants in liver disease.
- Understanding the interplay of genetic, epigenetic, and environmental factors is crucial for effective antioxidant therapy.
- Judicious use of antioxidants, considering potential toxicities and interactions, is recommended for hepatic disease management.
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