Related Experiment Video

Updated: Jul 5, 2025

Isolation and Characterization of Exosomes from Skeletal Muscle Fibroblasts
06:27

Isolation and Characterization of Exosomes from Skeletal Muscle Fibroblasts

Published on: May 16, 2020

3.4K

Retracted: Exosome: Function and Application in Inflammatory Bone Diseases

Oxidative Medicine And Cellular Longevity

    Oxidative Medicine and Cellular Longevity
    |January 18, 2024
    PubMed
    Summary

    This article has been retracted. The original publication is no longer considered valid scientific work.

    More Related Videos

    Large-Scale Preparation of Synovial Fluid Mesenchymal Stem Cell-Derived Exosomes by 3D Bioreactor Culture09:48

    Large-Scale Preparation of Synovial Fluid Mesenchymal Stem Cell-Derived Exosomes by 3D Bioreactor Culture

    Published on: July 26, 2022

    4.4K
    Labeling of Extracellular Vesicles for Monitoring Migration and Uptake in Cartilage Explants07:58

    Labeling of Extracellular Vesicles for Monitoring Migration and Uptake in Cartilage Explants

    Published on: October 4, 2021

    2.6K

    Related Concept Videos

    Overview of Exosomes01:36

    Overview of Exosomes

    Exosomes are stable, lipid bilayer-enclosed vesicles capable of crossing biological barriers. They can carry a wide range of molecules required for intercellular communication. Once exosomes are released from the cell where they originated, they enter a recipient cell through various pathways such as fusion, receptor-mediated endocytosis, macropinocytosis, and phagocytosis.
    Stahl et al. discovered exosomes in 1983, but the exosomes were initially considered waste products released from the...
    2.7K
    Osteoclasts in Bone Remodeling01:31

    Osteoclasts in Bone Remodeling

    Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
    2.9K
    Mesenchymal Stem Cells01:19

    Mesenchymal Stem Cells

    Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their...
    4.7K
    The Extracellular Matrix01:29

    The Extracellular Matrix

    Overview
    In order to maintain tissue organization, many animal cells are surrounded by structural molecules that make up the extracellular matrix (ECM). Together, the molecules in the ECM maintain the structural integrity of tissue as well as the remarkable specific properties of certain tissues.
    Composition of the Extracellular Matrix
    The extracellular matrix (ECM) is commonly composed of ground substance, a gel-like fluid, fibrous components, and many structurally and functionally diverse...
    9.0K
    Inflammatory Response01:28

    Inflammatory Response

    An inflammatory response is a localized, nonspecific immune reaction that occurs when a tissue is injured. It is characterized by redness, swelling, heat, and pain, which are commonly called the cardinal signs and symptoms of inflammation. Inflammation can sometimes result in a loss of function.
    Inflammation can be triggered by various stimuli, such as impact, abrasion, chemical irritation, infections, and extreme hot or cold temperatures. These can damage cells and connective tissue fibers,...
    2.0K
    Regulation of Hematopoietic Stem Cells01:01

    Regulation of Hematopoietic Stem Cells

    All blood and immune cells are produced from the multipotent hematopoietic stem cells (HSCs) by the process of hematopoiesis. However, they all have a limited life span. In addition, many are depleted in immune surveillance or combatting an injury or infection. This makes blood one of the most regenerative tissues. Hematopoiesis helps replenish these blood and immune cells, restoring the body's normal functioning. However, overproduction of blood and immune cells can make them cancerous or...
    3.2K