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Updated: Jul 5, 2025

Comparing the Affinity of GTPase-binding Proteins using Competition Assays
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Nucleocytoplasmic transport rates are regulated by cellular processes that modulate GTP availability

Kelsey L Scott1, Charles T Halfmann1, Allison D Hoefakker1,2

  • 1Enabling Technologies Group, Sanford Research, Sioux Falls SD.

Biorxiv : the Preprint Server for Biology
|January 18, 2024
PubMed
Summary

Cellular physiology changes, such as cell migration, affect GTP availability, which in turn modulates nucleocytoplasmic transport (NCT) rates. This impacts essential cellular functions like RNA export and protein synthesis.

Keywords:
GEVALGTPLINuSNucleocytoplasmic transportRan GTPaseglucocorticoid receptornuclear pore complex

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