Exposure and resistance to lantibiotics impact microbiota composition and function

Zhenrun J Zhang1, Cody Cole1, Huaiying Lin2

  • 1Duchossois Family Institute, University of Chicago, 900 E. 57th St, Chicago, IL 60637, USA; Department of Microbiology, Biological Sciences Division, University of Chicago, 5841 South Maryland Ave, Chicago, IL 60637, USA.

Summary

The study found that Lantibiotic Resistance System (LRS) genes are common in the human gut microbiome and help bacteria survive exposure to Nisin A, a food preservative. These genes impact bacterial fitness and host immune responses.

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