Moving towards the implementation of pharmacogenetic testing in Quebec

Area of Science:

• Pharmacogenetics
• Clinical implementation
• Genomic medicine

Background:

• Pharmacogenetics (PGx) testing offers reliable and affordable insights for personalized treatment decisions.
• Widespread clinical adoption of PGx in Canada is limited by several implementation barriers.
• Numerous successful global PGx implementation models exist.

Purpose of the Study:

• To identify and outline pharmacogenetics implementation barriers specific to Quebec, Canada.
• To propose efficient solutions for PGx integration, leveraging existing PGx clinics.
• To develop an adapted clinical implementation model for pharmacogenetics in Quebec.

Main Methods:

• Literature review of documented PGx implementation barriers in Quebec.
• Analysis of successful global PGx implementation strategies.
• Development of a proposed adapted clinical implementation model.

Main Results:

• Specific barriers to PGx implementation in Quebec have been identified.
• Potential solutions and strategies for overcoming these barriers have been suggested.
• An adapted clinical implementation model for Quebec has been proposed.

Conclusions:

• The province of Quebec possesses the necessary readiness for clinical pharmacogenetics implementation.
• The proposed model and solutions can facilitate the integration of PGx into routine care.
• Successful implementation of PGx in Quebec can enhance treatment decision-making.