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A fast and easy one-step purification strategy for plant-made antibodies using Protein A magnetic beads
Loïc Faye1, Clemens Grünwald-Gruber2, Louis-Philippe Vezina3
1ANGANY Innovation, 1 voie de l'innovation, Pharmaparc II, Val de Reuil, France.
Frontiers in Plant Science
|January 18, 2024
Abstract:
A major difficulty to reach commercial- scale production for plant-made antibodies is the complexity and cost of their purification from plant extracts. Here, using Protein A magnetic beads, two monoclonal antibodies are purified in a one-step procedure directly from non-clarified crude plant extracts. This technique provides significant savings in terms of resources, operation time, and equipment.
Keywords:
COVID - 19Nicotiana benthamianamagnetic bead purificationmonoclonal antibodyplant molecular farming
