A Case Report: Ovarian Fibrothecoma with Minor Sex Cord Elements
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Updated: Jul 5, 2025

Author Spotlight: Advancing Human Ovarian Repair and Cancer Studies with Surface Epithelium Organoids
Published on: August 16, 2024
Reina Miki1, Kazuhiro Kitajima2, Tetsuo Maeda3
1Department of Gynecology and Obstetrics, Chibune General Hospital, Osaka, Japan.
Introduction:
Ovarian stromal tumors with minor sex cord elements are rare, and there are not specific imaging features to help in making the diagnosis.
Case Presentation:
We report a case of this tumor in an 81-year-old woman who was referred to our hospital for constipation and a pelvic mass. Magnetic resonance imaging demonstrated a well-circumscribed mass and isointensity compared to the skeletal muscle on T1-weighted imaging (T1WI) and low signal intensity mixed with high signal ranges on T2-weighted imaging. Dynamic gadolinium-enhanced fat-suppressed T1WI revealed mild and increased enhancement of the peripheral area in the early and delayed phases, respectively. On diffusion-weighted imaging (DWI), a heterogeneously high signal intensity corresponding to the peripheral enhanced area was observed, and the apparent diffusion coefficient values of the high-intensity areas on DWI were low. Malignancy could be suspected, so the mass was surgically removed. Pathological assessment revealed a fibrothecoma with minor sex cord elements.
Conclusion:
The tumor's preoperative diagnosis is difficult, although the possibility of this rare tumor from atypical findings on DWI and/or dynamic contrast enhancement studies should be considered.
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