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[Choroidal changes in patients with diabetes mellitus].
A S Khalatyan1, Yu N Yusef1,2
1Krasnov Research Institute of Eye Diseases, Moscow, Russia.
Vestnik Oftalmologii
|January 18, 2024
Summary
Diabetic retinopathy (DR), a leading cause of vision loss, involves changes in the choroid. This review analyzes studies on choroidal thickness and vascularity in diabetes mellitus (DM) patients with DR, finding conflicting data.
Area of Science:
- Ophthalmology
- Endocrinology
- Medical Imaging
Background:
- Diabetic retinopathy (DR) is a major cause of global vision loss, stemming from diabetes mellitus (DM).
- The choroid, crucial for retinal health, may be affected by diabetic pathology, influencing DR development.
- Existing research on choroidal changes in DM, particularly DR, presents conflicting findings.
Approach:
- Systematic review of articles examining structural choroidal changes in diabetic patients.
- Focus on choroidal thickness (CT) and choroidal vascularity index (CVI) as markers.
- Analysis of studies correlating choroidal status with different stages of DR.
Key Points:
- Choroidal thickness (CT) and choroidal vascularity index (CVI) are key metrics for assessing choroidal vascularization.
- Conflicting data exists regarding choroidal thickness in diabetic patients, especially those with DR.
- The precise role of choroidal pathology in the pathogenesis of DR remains under investigation.
Conclusions:
- The relationship between structural choroidal alterations and diabetic retinopathy requires further clarification.
- A comprehensive understanding of choroidal status in DM patients is essential for managing DR.
- This review synthesizes current evidence to address the controversy surrounding choroidal changes in diabetic retinopathy.
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