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Idiopathic mesenteric phlebosclerosis combined with melanosis coli in a 51-year-old female

Tao Cai1, Bo Li2, Zhengxiong Li3

  • 1Endoscopy, The First People's Hospital in Shuangliu District/West China (Airport) Hospital.

Revista Espanola De Enfermedades Digestivas
|January 18, 2024
PubMed

Insights

Idiopathic mesenteric phlebosclerosis (IMP) and melanosis coli (MC) can coexist. Early diagnosis requires careful review of medication history, bowel preparation, and clinical observation to avoid misdiagnosis.

Area of Science:

  • Gastroenterology
  • Pathology
  • Colorectal diseases

Background:

  • Idiopathic mesenteric phlebosclerosis (IMP) is a rare condition causing ischemic colitis due to mesenteric vein calcification.
  • Melanosis coli (MC) is a benign pigmented mucosal lesion associated with laxative use, characterized by lipofuscin-laden macrophages.

Observation:

  • This report details a unique case where a patient presented with both idiopathic mesenteric phlebosclerosis and melanosis coli.
  • The co-occurrence of these distinct colorectal conditions presents diagnostic challenges.

Findings:

  • The study highlights the importance of recognizing the potential for concurrent IMP and MC.
  • Accurate diagnosis necessitates a comprehensive approach considering patient history and endoscopic findings.

Implications:

  • Clinicians must maintain a high index of suspicion for IMP, especially when MC is identified.
  • Thorough evaluation of medication history and bowel preparation is crucial for preventing missed IMP diagnoses in patients with MC.

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