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Updated: Jul 5, 2025

Biochemical Measurement of Neonatal Hypoxia

Biochemical Measurement of Neonatal Hypoxia

Published on: August 24, 2011

Decrease in lipid metabolic indexes in infants with neonatal respiratory distress syndrome.

Guohong Zheng¹, Jiansheng Zheng², Xiangrong Hu¹

¹Department of Pediatrics, The First Hospital of Putian, Putian, Fujian 351199, P.R. China.

Experimental and Therapeutic Medicine

|January 18, 2024

Summary

This summary is machine-generated.

Neonatal respiratory distress syndrome (NRDS) in premature infants is linked to lower plasma lipid levels, including triglyceride and calcium. These findings aid in managing NRDS and improving infant outcomes.

Keywords:

apolipoprotein cholesterol low-density lipoprotein neonatal respiratory distress syndrome triglycerides

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Last Updated: Jul 5, 2025

Biochemical Measurement of Neonatal Hypoxia

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Published on: August 24, 2011

Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics

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Non-invasive Optical Measurement of Cerebral Metabolism and Hemodynamics in Infants

Non-invasive Optical Measurement of Cerebral Metabolism and Hemodynamics in Infants

Published on: March 14, 2013

Area of Science:

Neonatology
Biochemistry
Pediatric Medicine

Background:

Neonatal respiratory distress syndrome (NRDS) is a serious condition in premature infants.
It is often caused by incomplete pulmonary function and insufficient surfactant production.
Understanding metabolic differences in NRDS infants is crucial for clinical management.

Purpose of the Study:

To compare lipid metabolism indexes and clinical information between infants with and without NRDS.
To identify potential risk factors associated with NRDS.
To provide data for guiding the clinical management of NRDS.

Main Methods:

Retrospective comparison of clinical data and plasma biochemical/lipid indexes.
Involved 79 NRDS infants and 44 non-NRDS infants.
Used inverse probability of treatment weighting (IPTW) analysis and multivariate logistic analysis.

Main Results:

NRDS infants had lower body weight and gestational age.
Significantly lower plasma levels of triglyceride, cholesterol, LDL, thyroid hormones, glucose, calcium, and phosphorus were observed in NRDS infants.
NRDS infants showed higher rates of pneumonia, sepsis, brain injury, preterm birth, and congenital heart defects.

Conclusions:

Infants with NRDS exhibit significantly lower plasma lipid profiles.
Triglyceride and calcium levels are identified as risk factors for NRDS.
These findings support targeted clinical interventions for NRDS management.