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Mpox Outbreak - Los Angeles County, California, May 4-August 17, 2023.
MMWR. Morbidity and Mortality Weekly Report
|January 18, 2024
Summary
Mpox cases increased in Los Angeles County in May 2023, though the outbreak was smaller than in 2022. Vaccination and prior infections likely contributed to lower case numbers, but mpox still spreads.
Area of Science:
- Epidemiology
- Infectious Diseases
- Public Health
Background:
- Los Angeles County (LAC) reported approximately 2,500 mpox cases since May 2022.
- A notable increase in mpox cases was observed from May to August 2023 after a period of low incidence.
Purpose of the Study:
- To analyze the characteristics and trends of the mpox outbreak in LAC during May-August 2023.
- To compare the 2023 outbreak to the 2022 mpox epidemic in LAC.
Main Methods:
- Retrospective analysis of mpox case data reported to the LAC Department of Public Health.
- Epidemiological investigation of case demographics, vaccination status, and transmission patterns.
Main Results:
- 56 mpox cases were identified between May 4 and August 17, 2023.
- Most cases involved men who have sex with men, similar to the 2022 outbreak.
- Only 29% of patients were fully vaccinated, with one hospitalization and no deaths. Two mild reinfections occurred.
Conclusions:
- The 2023 mpox outbreak in LAC was significantly smaller than the 2022 outbreak, potentially due to increased population immunity from vaccination and prior infections.
- Mpox continues to circulate in LAC, underscoring the need for ongoing preventive measures, including JYNNEOS vaccination for at-risk individuals.
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