Impact of segmented optical axial length on the performance of intraocular lens power calculation formulas
So Goto1, Naoyuki Maeda, Kazuhiko Ohnuma
1From the Department of Ophthalmology, National Hospital Organization, Tokyo Medical Center, Meguro-ku, Tokyo, Japan (Goto, Ogawa, Sugiyama, Matsumaru, Noda); Department of Ophthalmology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan (Goto, Maeda); Herbert Wertheim School Optometry and Vision Science, University of California, Berkeley, California (Goto); Laboratorio de Lente Verde, Sodegaura, Chiba, Japan (Ohnuma); VO, Toda, Saitama, Japan (Lawu).
Purpose:
To investigate the difference between the segmented axial length (AL) and the composite AL on a swept-source optical coherence tomography biometer and to evaluate the subsequent effects on artificial intelligence intraocular lens (IOL) power calculations: the Kane and Hill-RBF 3.0 formulas compared with established vergence formulas.
Setting:
National Hospital Organization, Tokyo Medical Center, Japan.
Design:
Retrospective case series.
Methods:
Consecutive patients undergoing cataract surgery with a single-piece IOL were reviewed. The prediction accuracy of the Barrett Universal II, Haigis, Hill-RBF 3.0, Hoffer Q, Holladay 1, Kane, and SRK/T formulas based on 2 ALs were compared for each formula. The heteroscedastic test was used with the SD of prediction errors as the endpoint for formula performance.
Results:
The study included 145 eyes of 145 patients. The segmented AL (24.83 ± 1.89) was significantly shorter than the composite AL (24.88 ± 1.96, P < .001). Bland-Altman analysis revealed a negative proportional bias for the differences between the segmented AL and the composite AL. The SD values obtained by Hoffer Q, Holladay 1, and SRK/T formulas based on the segmented AL (0.52 diopters [D], 0.54 D, and 0.50 D, respectively) were significantly lower than those based on the composite AL (0.57 D, 0.60 D, and 0.52 D, respectively, P < .01).
Conclusions:
The segmented ALs were longer in short eyes and shorter in long eyes than the composite ALs. The refractive accuracy can be improved in the Hoffer Q, Holladay 1, and SRK/T formulas by changing the composite ALs to the segmented ALs.
Related Concept Videos
Focusing of Light in the Eye
Imaging Biological Samples with Optical Microscopy
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
Relation between Poisson's ratio, Modulus of Elasticity and Modulus of Rigidity
Thin-Walled Hollow Shafts
General Case of Eccentric Axial Loading
Consider a member subjected to equal and opposite forces that are applied along a line that does not coincide with the member's neutral axis. In unsymmetrical...
Eccentric Axial Loading in a Plane of Symmetry


