Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Antibiotic Selection

Antibiotic Selection

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Breaking Barriers Between Species: Integrated Multi-Species PK Models Improve Human PK Predictions.

CPT: pharmacometrics & systems pharmacology·2026

Same author

Pneumonia due to Mycobacterium shimoidei: a rare non-tuberculous mycobacterial infection in a young patient with anorexia nervosa.

Infection·2026

Same author

Increase in imported mupirocin-resistant <i>Staphylococcus aureus</i> from the tropics and subtropics: trends in Berlin from 2018 to 2025.

New microbes and new infections·2026

Same author

Review of Existing Approaches and Potential Role of Pharmacometrics in the Interpretation of Prognostic Circulating Serum Biomarkers in Advanced NSCLC.

Clinical and translational science·2026

Same author

Tachykinin-related peptide signalling is important for the immune response of the mealworm beetle <i>Tenebrio molitor</i> L.

Frontiers in immunology·2026

Same author

Viral Simulation Reveals Overestimation Bias in Within-Host Phylodynamic Migration Rate Estimates Under Selection.

Molecular biology and evolution·2026

Same journal

Environmental microbes as modulators of plant volatile landscapes: Implications for plant-insect chemical communication.

Trends in microbiology·2026

Same journal

Beyond AMGs: Phage-encoded transcription and sigma factors as understudied virocell reprogramming tools.

Trends in microbiology·2026

Same journal

Cronobacter spp.

Trends in microbiology·2026

Same journal

Anaerobic lignin deconstruction: A game changer for lignocellulosic biorefineries.

Trends in microbiology·2026

Same journal

Critical role of the inflammatory rheostat in influenza-associated pulmonary aspergillosis.

Trends in microbiology·2026

Same journal

Structure-based prokaryotic transcription shapes adaptation and host-invader interplay.

Trends in microbiology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jul 5, 2025

Quantification of Plasmid-Mediated Antibiotic Resistance in an Experimental Evolution Approach

Quantification of Plasmid-Mediated Antibiotic Resistance in an Experimental Evolution Approach

Published on: December 14, 2019

Forecasting antimicrobial resistance evolution.

Jens Rolff¹, Sebastian Bonhoeffer², Charlotte Kloft³

¹Evolutionary Biology, Institute of Biology, Freie Universität Berlin, Berlin, Germany.

Trends in Microbiology

|January 18, 2024

Summary

This summary is machine-generated.

Forecasting antimicrobial resistance (AMR) can combat the antibiotic crisis by guiding sustainable drug use, reducing resistance gene spread, and enabling efficient infection treatment. This proactive approach requires new technology and a mindset shift.

Keywords:

AMR antibiotics forecasting prediction resistance evolution stakeholders

More Related Videos

Testing the Role of Multicopy Plasmids in the Evolution of Antibiotic Resistance

Testing the Role of Multicopy Plasmids in the Evolution of Antibiotic Resistance

Published on: May 2, 2018

Author Spotlight: Understanding and Detecting Environmental Antimicrobial Resistance by Combining Culture-Based Techniques and Genomics

Author Spotlight: Understanding and Detecting Environmental Antimicrobial Resistance by Combining Culture-Based Techniques and Genomics

Published on: July 19, 2024

Related Experiment Videos

Last Updated: Jul 5, 2025

Quantification of Plasmid-Mediated Antibiotic Resistance in an Experimental Evolution Approach

Quantification of Plasmid-Mediated Antibiotic Resistance in an Experimental Evolution Approach

Published on: December 14, 2019

Testing the Role of Multicopy Plasmids in the Evolution of Antibiotic Resistance

Testing the Role of Multicopy Plasmids in the Evolution of Antibiotic Resistance

Published on: May 2, 2018

Author Spotlight: Understanding and Detecting Environmental Antimicrobial Resistance by Combining Culture-Based Techniques and Genomics

Author Spotlight: Understanding and Detecting Environmental Antimicrobial Resistance by Combining Culture-Based Techniques and Genomics

Published on: July 19, 2024

Area of Science:

Microbiology
Public Health
Pharmacology

Background:

Antimicrobial resistance (AMR) poses a significant global health threat.
Current strategies focus on drug stewardship, new drug development, and diagnostics.
Forecasting the evolution of resistance remains an under-addressed area.

Purpose of the Study:

To highlight the potential of forecasting as a crucial tool against AMR.
To outline how resistance forecasting can mitigate the antibiotic crisis.
To identify key challenges for implementing resistance forecasting.

Main Methods:

Conceptual analysis and argumentation.
Literature review on AMR and forecasting methodologies.
Identification of technological and mindset-related barriers.

Main Results:

Forecasting can extend antibiotic lifespan and incentivize drug development.
It can reduce the environmental and inter-patient spread of AMR.
Forecasting enables better treatment of persistent infections, curbing further resistance evolution.

Conclusions:

Successful AMR forecasting requires novel technologies for risk assessment.
A paradigm shift from reactive to proactive resistance management is essential.
Implementing forecasting will significantly enhance global efforts to combat AMR.