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PRDM16 regulates γδT17 cell differentiation via controlling type 17 program and lipid-dependent cell fitness

Jinwoo Nah1, Youngjin Lee1, Rho H Seong1

  • 1School of Biological Sciences, Institute of Molecular Biology and Genetics, Seoul National University, Seoul, Republic of Korea.

Frontiers in Immunology
|January 19, 2024
PubMed
Summary

PRDM16 regulates γδT17 cell differentiation and function. Loss of PRDM16 enhances γδT17 cell fitness and immunity, potentially impacting inflammatory diseases like psoriasis.

Keywords:
PRDM16lipidlipid-dependent cell fitnesspsoriasisγδT17 cell

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