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Emicizumab and asparaginase, A first experience to share

Laurie Goubeau1, Cécile Bally2, Delphine Borgel1,3

  • 1Laboratoire d'Hématologie Biologique, AP-HP, Hôpital Necker Enfants Malades, Paris, France.

Haemophilia : the Official Journal of the World Federation of Hemophilia
|January 19, 2024
PubMed
Abstract

No abstract available in PubMed .

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Neurokinin 1 (NK1) receptors are distributed across the GI tract, vagal afferents, and key CNS regions including the central vomiting center and chemoreceptor trigger zone (CTZ) Chemotherapy agents stimulate enterochromaffin cells in the gastrointestinal (GI) tract to release large amounts of substance P (SP). SP is a neuropeptide released by specific sensory nerves in response to many different stressors, including those in the GI mucosa affected by chemotherapy.  SP binds and activates...
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