Hypertrophic pulmonary osteoarthropathy and breast cancer

Hypertrophic pulmonary osteoarthropathy is an uncommon, poorly understood syndrome usually seen with bronchogenic carcinomas, and rarely with tumors metastatic to the lungs or mediastinum. In a review of the literature, we have found only 140 cases associated with nonbronchogenic intrathoracic tumors. We have reported a case associated with metastatic breast carcinoma in which surgical resection led to rapid disappearance of the syndrome and prolonged palliation for the patient.