Related Experiment Video
Updated: Jul 5, 2025

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
Published on: August 7, 2017
Association Between Exclusive Breastfeeding and Acute Respiratory Infections Among Infants Under the Age of 6 Months
Nada H Farrag1, Zelalem T Haile2, Gillian Ice3
1Clinical Pharmacy, School of Life and Medical Sciences, University of Hertfordshire Hosted by Global Academic Foundation, New Administrative Capital, Egypt.
Insights
Exclusive breastfeeding significantly reduces the risk of acute respiratory infection (ARI) in infants under six months. This finding highlights the protective role of exclusive breastfeeding in low- and middle-income countries.
Area of Science:
- Pediatrics
- Public Health
- Epidemiology
Background:
- Acute respiratory infection (ARI) is a primary cause of illness and death in children globally.
- Exclusive breastfeeding is crucial for infant health but remains suboptimal in low- and middle-income countries (LMICs).
Purpose of the Study:
- To determine the association between exclusive breastfeeding and ARI in infants younger than six months in an LMIC.
Main Methods:
- Secondary analysis of the 2014 Egypt Demographic Health Survey data.
- Included 1,340 mothers with infants under six months.
- Defined ARI by maternal report of cough with rapid or difficult breathing; exposure was exclusive breastfeeding.
Main Results:
- 41% of infants were exclusively breastfed; 9% experienced ARI symptoms.
- Exclusive breastfeeding was associated with a reduced likelihood of ARI (AOR=0.450).
- Maternal age and infant age were also significant factors influencing ARI risk.
Conclusions:
- Exclusive breastfeeding offers protection against ARI symptoms in infants under six months.
- Findings are independent of other potential confounding factors.
- Promoting exclusive breastfeeding is vital for reducing childhood ARI in LMICs.
Abstract:
Acute respiratory infection (ARI) is the leading cause of childhood morbidity and mortality. Exclusive breastfeeding is considered the cornerstone of child health; however, the rate of exclusive breastfeeding is suboptimal in low- and middle-income countries (LMICs). This study aimed to assess the association between exclusive breastfeeding and ARI among infants under the age of 6 months in a LMIC. A secondary analysis of the 2014 Egypt Demographic Health Survey data was conducted. Mothers of infants under the age of 6 months (n = 1,340) were included. The outcome of interest was ARI symptoms among infants, defined by mother's report of a cough accompanied by fast or difficult breathing in the 2 weeks preceding the survey. The exposure variable was exclusive breastfeeding, defined by giving infants only breast milk during the first 6 months of life. Descriptive statistics and multivariate regression were performed. Forty-one percent of the infants were exclusively breastfed and 9% had ARI symptoms. Exclusive breastfeeding reduced the odds of ARI symptoms (adjusted odds ratio [AOR] = 0.450, 95% confidence interval [CI]: 0.243-0.832). Infants of mothers 20-34 years of age (AOR = 0.421, 95% CI: 0.217-0.817) and ≥35 years (AOR = 0.308, 95% CI: 0.123-0.767) at childbirth were less likely to have symptoms of an ARI when compared with adolescent mothers. The likelihood of having ARI symptoms was higher among infants 2-3 months of age (AOR = 2.437, 95% CI: 1.093-5.435), and 4-5 months (AOR = 2.888, 95% CI: 1.193-6.992) compared with infants less than 2 months. Exclusive breastfeeding was protective against ARI symptoms among under-6-month infants, independent of potential confounders.
Related Concept Videos
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Acute Respiratory Failure-V
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Development of Immunocompetence
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
Pulmonary Cycle: Exhalation
Respiratory Assessment: Purpose and Indications
Objectives and Importance:
The primary goal of respiratory assessment is to evaluate patients at early risk of clinical deterioration. Since respiratory distress often precedes other signs of declining health, breathing patterns and sounds become a...
Breathing

