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Incidental meningiomas in autopsy study
Abstract:
Two hundred thirty-one cases of incidental meningiomas found at autopsy at the Montefiore Medical Center during the period from 1950 to 1982 were reviewed. The prevalence of incidental meningiomas increased with age, and was highest in people 80 years of age or older. The male to female ratio was 1 to 3. The relative size of the tumors also increased with age. Multiple meningiomas were found in 8.2% of the cases; none of them had stigmata of neurofibromatosis.
Insights
Incidental meningiomas, benign brain tumors found unexpectedly, increase with age, particularly in those over 80. This autopsy study found a 1:3 male to female ratio and larger tumors in older individuals.
Area of Science:
- Neuropathology
- Geriatric Medicine
- Oncology
Background:
- Incidental meningiomas are frequently discovered during autopsies.
- Understanding their prevalence and characteristics is crucial for geriatric and neurosurgical care.
Purpose of the Study:
- To analyze the prevalence, demographics, and characteristics of incidental meningiomas.
- To investigate the relationship between age and meningioma size and occurrence.
Main Methods:
- Retrospective review of 231 autopsy cases with incidental meningiomas.
- Data collected from Montefiore Medical Center between 1950 and 1982.
- Analysis of tumor prevalence, size, and patient demographics (age, sex).
Main Results:
- Prevalence of incidental meningiomas increased with age, peaking in individuals 80 years and older.
- A male to female ratio of 1:3 was observed.
- Tumor size also showed a positive correlation with age.
- Multiple meningiomas occurred in 8.2% of cases, without neurofibromatosis stigmata.
Conclusions:
- Age is a significant factor in the prevalence and size of incidental meningiomas.
- Findings highlight the importance of considering age-related changes in meningioma occurrence.
- The study provides valuable epidemiological data on incidental meningiomas in an elderly population.