Visible-Light-Driven Multicomponent Diamination and Oxyamination of Alkene
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Updated: Jul 5, 2025

Light-driven Enzymatic Decarboxylation
Published on: May 22, 2016
Mengping He1,2, Chengcheng Shi1,2, Mengqi Luo2
1College of Chemical and Material Engineering, Quzhou University, Quzhou 324000, China.
Abstract:
Herein, we describe an effective method for the synthesis of 2-alkoxyamides and 1,2-diamines through visible-light-mediated difunctionalization of alkenes. N-Aminopyridinium salts were employed as appropriate precursors to generate key amidyl radical intermediates via a photoinduced single-electron transfer (SET) process. The amidyl radicals would react with alkenes, followed by oxidation and nucleophilic addition. Excellent functional group tolerance and good yields demonstrate the synthetic potential of this transformation.
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