Related Experiment Video
Updated: Jul 5, 2025

A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit
Published on: July 13, 2019
Reducing Procedural Pain and Avoiding Peripheral Intravenous Catheters by Implementing a Feeding Protocol for Late
Jennifer Hanford1, Christine McQuay, Akshaya Vachharajani
1Neonatal Intensive Care Unit, University of Missouri Healthcare, Women's Hospital, Columbia.
Insights
Implementing a new feeding protocol for late preterm infants significantly reduced the need for intravenous (IV) access and starter parenteral nutrition (PN), decreasing infant pain. This approach optimizes nutrition for this vulnerable population.
Area of Science:
- Neonatal Medicine
- Pediatric Nutrition
- Quality Improvement Science
Background:
- Late preterm births represent a substantial proportion of all preterm deliveries.
- Optimal nutritional strategies and enteral feeding methods for late preterm infants are not well-established, often leading to reliance on intravenous (IV) fluids.
- Current practices may involve unnecessary IV access and starter parenteral nutrition (PN).
Purpose of the Study:
- To create and implement a feeding protocol for late preterm infants.
- The primary goals were to reduce the requirement for IV access, minimize the use of starter PN, and alleviate pain in neonatal intensive care unit (NICU) infants.
- To enhance the care and outcomes for late preterm infants.
Main Methods:
- The Plan-Do-Study-Act (PDSA) quality improvement model served as the framework.
- A comprehensive literature review informed the development of a feeding protocol emphasizing judicious starter PN use.
- The protocol was implemented, evaluated, and refined, including the addition of electronic medical record auto-text reminders.
Main Results:
- The protocol implementation led to a significant reduction in peripheral IV access, decreasing from 70% to 42% (P = .0017).
- There was a substantial decrease in the initiation of starter PN, from 55% to 7% (P < .00001).
- These reductions were achieved without significant adverse effects on other clinical measures, and infant pain was lessened.
Conclusions:
- Initiating enteral feedings upon admission for stable, late preterm infants is an effective strategy.
- This approach successfully reduces the need for peripheral IV access.
- Consequently, the implementation of this protocol decreases procedural pain for infants.
Background:
Late preterm births account for a large portion of preterm births, yet the optimal method of nutrition and enteral feeding in this population remains unclear and often involves intravenous (IV) fluids.
Purpose:
To develop and implement a late preterm feeding protocol in order to decrease the necessity of IV access, decrease the use of starter parenteral nutrition (PN), and reduce the pain endured by an infant in the neonatal intensive care unit.
Methods:
The Plan-Do-Study-Act quality improvement model was utilized as a framework for the implementation of this quality improvement project. A literature review was conducted and subsequently, a feeding protocol was developed and included the more judicious use of starter PN. This protocol was implemented, evaluated, and adopted. A second Plan-Do-Study-Act cycle was completed with the addition of an auto-text reminder incorporated into admission notes in the electronic medical record.
Results:
The implementation of the protocol significantly reduced placement of IV access and the use of starter (PN) in late preterm infants without considerable differences in balancing measures. The percentage of infants who received peripheral IV access declined considerably from 70% to 42% ( P = .0017) subsequently, less pain endured by the infants. There was a decrease in the initiation of starter PN from 55% to 7% ( P < .00001).
Implications For Practice:
Administering enteral feedings on admission to stable, late preterm infants reduced the need for peripheral IV access and thus decreased pain from this procedure.
Related Concept Videos
Parentral Nutrition: Centeral and Peripheral Parental Nutrition
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
Enteral Nutrition I: Orogastric and Nasogastric Feeding
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...

